Published peer reviewed papers and publications  with EPIZONE acknowledgement

WP 4.1 Real-time PCR-diagnostics

Cêtre-Sossah C, Mathieu B, Setier-Rio ML, Grillet C, Baldet T, Delecolle JC, Albina E. (2008), Development and evaluation of a real-time quantitative PCR assay for Culicoides imicola, one of the main vectors of bluetongue (BT) and African horse sickness (AHS) in Africa and Europe. Research in Veterinary Science, 85, 372–385

WP 4.2 DNA Chip-based diagnostics

Peter Gyarmati, Tim Conze, Siamak Zohari, Neil LeBlanc, Mats Nilsson, Ulf Landegren,

Johan Baner and Sandor Belak (2008). Simultaneous Genotyping of All Hemagglutinin and Neuraminidase Subtypes of Avian Influenza Viruses by Use of Padlock Probes. JOURNAL OF CLINICAL MICROBIOLOGY, 2008, 1747–1751

Astrid Gall, Bernd Hoffmann, Timm Harder, Christian Grund and Martin Beer (2008),

Universal primer set for amplification and sequencing of HA0 cleavage sites of all influenza A viruses. J. Clin. Microbiol. 46, 2561-2567

LeBlanc N, Gantelius J, Schwenk JM, Ståhl K, Blomberg J, Andersson-Svahn H and Belak S (2009) Development of a magnetic bead microarray for the simultaneous and simple detection of four pestivirus, J Virol Methods.155(1):1-9.

Gall A, Hoffmann B, Harder T, Grund C, Höper D, Beer M (2009) Design and validation of a microarray

for detection, hemagglutinin subtyping, and pathotyping of avian influenza viruses. J Clin Microbiol. 2009 Feb;47(2):327-334.

Gall A, Hoffmann B, Harder T, Grund C, Ehricht R, Beer M. (2009) Rapid haemagglutinin subtyping and pathotyping of avian influenza viruses by a DNA microarray. J Virol Methods  2009 May 14.

WP 4.3 DIVA diagnostics

Parida, S (2009) Vaccination against foot-and-mouth disease virus: Strategies and effectiveness. Expert Rev. Vaccines 8(3), 347-365.

Leifer, E., Depner, K, Blome, S, Le Potier,M-F; Le Dimna, M., Beer, M., Hoffmann, B (2009) Differentiation of C-strain “Riems” of CP7_E2alf vaccinated animals from animals infected by classical swine fever virus field strains using real-time RT-PCR. J.Vir.Meth 158, 114-122.

WP 4.4 Pen-side tests

Michaud et al., (2007) “Long-term storage at tropical temperature of dried-blood filter papers for detection and genotyping of RNA and DNA viruses by direct PCR” Journal of Virological Methods, 146, 257-265.

WP 5.1 Vaccine technologies

Rodolphe Gravier, Daniel Dory, Michel Laurentie , Stéphanie Bougeard, Roland Cariolet, André Jestin (2007), In vivo tissue distribution and kinetics of a pseudorabies virus plasmid DNA vaccine after intramuscular injection in swine. Vaccine 25, 6930–6938

Anne Prel, Ghislaine Le Gall-Reculé, Véronique Jestin (2008) Achievement of avian influenza virus-like particles that could be used as a subunit vaccine against low-pathogenic avian influenza strains in ducks. Avian Pathology 37(5), 513-520.

Eva Calvo-Pinilla, Teresa Rodríguez-Calvo, Juan Anguita, Noemí Sevilla, Javier Ortego. (2009) Establishment of a Bluetongue Virus Infection Model in Mice that Are Deficient in the Alpha/Beta Interferon Receptor. PLoS ONE 4(4): e5171.

Keil, G.M., Klopfleisch, C., Giesow, K., Blohm, U (2009)  Novel vectors for simultaneous high-level dual protein expression in vertebrate and insect cells by recombinant baculoviruses. Journal of Virological Methods doi:10.1016.

Keil GM. Modified bovine herpesvirus 1 for protein secretion. (2009) Methods Mol Biol.;515:249-60.

WP 5.2 Host responses to infection

Vahlenkamp, T.W., T.C. Harder, M. Giese, F. Lin, J.P. Teifke, R. Klopfleisch, R. Hoffmann, I. Tarpey, M. Beer, and T.C. Mettenleiter (2008): Protection of cats against lethal influenza H5N1 challenge infection. J. Gen. Virol. 89, 968-974.

Giese, M., T.C. Harder, J. Teifke, R. Klopfleisch, A. Breithaupt, T. Mettenleiter, and T.W. Vahlenkamp (2008): Experimental infection and natural contact exposure of dogs with H5N1 avian influenza virus. Emerg. Infect. Dis. 14, 308-310.

Eva Calvo-Pinilla, Teresa Rodríguez-Calvo, Juan Anguita, Noemí Sevilla, and Javier Ortego (2009). Establishment of a Bluetongue Virus Infection Model in Mice that Are Deficient in the Alpha/Beta Interferon Receptor. PLoS ONE 4(4): e5171.

Marta Sanz-Ramos, Fayna Díaz-San Segundo, Cristina Escarmís, Esteban Domingo, and Noemí Sevilla (2008). Hidden virulence determinants in a viral quasispecies in vivo. J. Virol. 82 (21):10465-10476.

Rebecca J. Rowlands, Vincent Michaud, Livio Heath, Geoff Hutchings, Chris Oura, Wilna Vosloo, Rahana Dwarka, Tinatin Onashvili, Emmanuel Albina, and Linda K. Dixon (2008). African Swine Fever Virus Isolate, Georgia, 2007. Emerg Infect Dis.  14(12): 1870–1874.

WP 5.3 Adjuvants and immunomodulators

Brandhonneur N, Chevanne F, Vié V, Frisch B, Primault R, Le Potier MF, Le Corre P., Specific and non-specific phagocytosis of ligand-grafted PLGA microspheres by macrophages, Eur J Pharm Sci. 2009 Mar 2;36(4-5):474-85. Epub 2008 Dec 6.

Montero J, Estepa A, Coll J, Tafalla C. Regulation of rainbow trout (Oncorhynchus mykiss) interleukin-8 receptor (IL-8R) gene transcription in response to viral hemorrhagic septicemia virus (VHSV), DNA vaccination and chemokines. Fish Shellfish Immunol. 2008 Sep;25(3):271-80.

Montero J, Coll J, Sevilla N, Cuesta A, Bols NC, Tafalla C.  Interleukin 8 and CK-6 chemokines specifically attract rainbow trout (Oncorhynchus mykiss) RTS11 monocyte-macrophage cells and have variable effects on their immune functions. Dev Comp Immunol. 2008;32(11):1374-84.

WP 5.4 Antivirals

Goris N, Vandenbussche F, De Clercq K. (2008) Potential of antiviral therapy and prophylaxis for controlling RNA viral infections of livestock. Antivir. Res. 78, 170-178.

Harmsen MM, Fijten HP, Dekker A, Eblé PL.(2008) Passive immunization of pigs with bispecific llama single-domain antibody fragments against foot-and-mouth disease and porcine immunoglobulin. Vet Microbiol., doi:10.1016/j.vetmic.2008.04.030.

Vrancken, R., Haegeman, A. , Paeshuyse, J, Puerstinger, G., Rozenski, J., Wright, M., Tignon, M., Le Potier, M.F., Neyts, J., Koenen, F. 2009, A proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor. J Gen Virol. 2009 Jun;90(Pt 6):1335-42. Epub 2009 Mar 4

Harmsen, M.M., Fijten, H.P.D., Engel, B., Dekker, A., Eblé, P.L. 2009. Passive immunization with llama single-domain antibody fragments reduces foot-and-mouth disease transmission between pigs. Vaccine, 27 (13): 1904-1911

Vrancken, R., Haegeman, A., Dewulf, J., Paeshuyse, J., Puerstinger, G., Tignon, M., Le Potier, M.-F., Neyts, J., Koenen, F. The reduction of CSFV transmission to untreated pigs by the antipestiviral compound BPIP: a proof of concept. Vet Microbiol. 2009 Jun 21. [Epub ahead of print]

Keita, D., Servan de Almeida, R., Libeau, G., Albina, E. 2008. Identification and mapping of a region on the mRNA of Morbillivirus nucleoprotein susceptible to RNA interference. Antiviral Res., 80(2):158-67.

WP 6.1 Surveillance and Epidemiology of emerging viral diseases in aquaculture

Strarick et al, 2008. Phylogenetic analyses of highly pathogenic avian influenza virus isolates from Germany in 2006 and 2007 suggest at least three separate introductions of H5N1 virus. Vet. Microbiol 128, 243-252.

Fusaro A, Joannis T, Monne I, Salviato A, Yakubu B, Meseko C, Oladokun T, Fassina S, Capua I, Cattoli G (2009). Introduction into Nigeria of a distinct genotype of avian influenza virus (H5N1). Emerg Infect Dis. 15:445-7.

István Kiss, Péter Gyarmati, Siamak Zohari, Karin Wilbe Ramsay, Giorgi Metreveli, Elisabeth Weiss, Maria Brytting, Marielle Stivers, Sofia Lindström, Ake Lundkvist, Kirill Nemirov, Peter Thorén, Mikael Berg, György Czifra, Sándor Belák (2009) Molecular characterization of highly pathogenic H5N1 avian influenza viruses isolated in Sweden in 2006. J Virol Methods 5:113

WP 6.3 Experimental Epidemiology

Eblé PL, de Koeijer AA, de Jong MCM, Engel B, Dekker A (2008) A meta-analysis quantifying transmission parameters of FMDV strain O Taiwan among non-vaccinated and vaccinated pigs. Prev Vet Med; 98-106.

Goris NE, Eblé PL, de Jong MCM, de Clercq K (2009). Quantifying foot-and-mouth disease virus transmission rates using published data. ALTEX 26; 1/09: 52-54.

WP 6.4 Molecular Epidemiology

Bréard E, Corrine Sailleau, Kyriaki Nomikou, Chris Hamblin, Peter Mertens, Philip S Mellor, Medhi El Harrach, Stéphan Zientara. 2007. Molecular epidemiology of serotype 4 bluetongue viruses isolated in the Mediterranean Basin between 1979 and 2004. Virus Research, in press, (2007 Feb 2; [Epub ahead of print]).

Michaud, V., Gil, P., Kwiatek, O., Prome, S., Dixon, L., Romero, L., Le Potier, M. F., Arias, M., Couacy-Hymann, E., Roger, F., Libeau, G. & Albina, E. (2007). Long-term storage at tropical temperature of dried-blood filter papers for detection and genotyping of RNA and DNA viruses by direct PCR. J Virol Methods 146, 257-265.

L.M. McElhinney, D.A. Marston, S. Stankov, C. Tu, C. Black, N. Johnson, Y. Jiang, N. Tordo, T. Müller, A.R. Fooks. Molecular Epidemiology of Lyssaviruses in Eurasia. DevBiol. Basel, Karger, 2008, vol131, pp125-131

Klein J, Hussain M, Ahmad M, Afzal M, Alexandersen S. (2008)

Epidemiology of foot-and-mouth disease in Landhi Dairy Colony, Pakistan, the world largest Buffalo colony. Virol J. doi:10.1186/1743-422X-5-53

Aboubakar Yaya, LucíaManso-Silvan, Alain Blanchard, François Thiaucourt (2008)

Genotyping of Mycoplasma mycoides subsp. mycoides SC by multilocus sequence analysis allows molecular epidemiology of contagious bovine pleuropneumonia

Vet. Res. doi: 10.1051/vetres:2007052